Impact of Linked Color Imaging on Sessile Serrated Lesion Miss Rate

Starting soon · Not applicable

Conditions studied: Colorectal Sessile Serrated Lesion

In brief

This prospective, multicenter randomized controlled trial aimed to investigate whether linked color imaging (LCI) could reduce the miss rate of sessile serrated lesions (SSLs) during tandem colonoscopy compared with conventional white-light imaging (WLI).

Key facts

Study ID

NCT07745842

Run by

Nanfang Hospital, Southern Medical University

People needed

2072

Starts

2026-08-01

Expected to finish

2029-02-01

Last updated by the study team

2026-08-04

Who can join

Age: 45 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Subjects aged ≥45 years, regardless of gender;
• Subjects undergoing screening colonoscopy;
• Subjects with no prior colonoscopy;
• Voluntarily provide written informed consent.

You may not qualify if…

• Subjects unable to cooperate with or tolerate colonoscopy;
• Subjects with inflammatory bowel disease;
• Known or highly suspected colorectal obstruction;
• History of colorectal surgery;
• Chronic recurrent constipation;
• Failure to discontinue anticoagulants or antiplatelet agents for at least 1 week before the procedure;
• Poor bowel preparation with an inadequate Aronchick scale score during colonoscopy;
• Failed cecal intubation;
• High-risk conditions including severe cardiovascular and cerebrovascular diseases, uncorrected severe anemia or active infection;
• Pregnant or breastfeeding women;
• Subjects deemed ineligible for participation in this trial at the investigator's discretion.

Full record on ClinicalTrials.gov

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