Vasoactive Inotropic Score in Adult Cardiac Surgery Outcomes
Completed
Conditions studied: Cardiac Surgical Procedures, Cardiac Surgical Procedures (Postoperative Population)
In brief
This study looked at whether a bedside score called the Vasoactive Inotropic Score (VIS) could help doctors predict which adult patients are at higher risk of complications after heart surgery that uses a heart-lung machine (cardiopulmonary bypass). VIS is calculated from the doses of heart-support medications a patient is already receiving after surgery, so it does not require any extra tests or procedures. Researchers measured VIS at five points in the first two days after surgery in 232 adults undergoing a range of heart operations, including valve surgery and coronary artery bypass. The study found that VIS measured soon after surgery, and again at 24 hours, gave useful early warning of which patients were more likely to experience serious complications such as kidney injury, stroke, or the need for additional circulatory support. This information could help hospital teams identify at-risk patients earlier and monitor them more closely.
Key facts
- Study ID
- NCT07745283
- Run by
- Sir Ganga Ram Hospital
- People needed
- 617
- Starts
- 2018-10-01
- Expected to finish
- 2022-06-30
- Last updated by the study team
- 2026-08-04
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age 18 years or older
- Undergoing elective or semi-elective cardiac surgery with cardiopulmonary bypass (CPB)
You may not qualify if…
- Required CPB solely for extracorporeal membrane oxygenation (ECMO)
- Pre-operative left ventricular assist device (LVAD) in situ
- Pre-operative intra-aortic balloon pump (IABP) support
- Declined to provide consent
Where it is running
- Sir Ganga Ram Hospital — Delhi, National Capital Territory of Delhi, India
Full record on ClinicalTrials.gov
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