Validation of Serum Metabolite Differences in Patients With Gallstones and Gallbladder Cancer
Completed
Conditions studied: Gallstone Disease, Gallbladder Malignant Neoplasm
In brief
We have observed that the serum levels of certain metabolites differ between Chilean patients with gallbladder cancer and those with gallstone disease. Based on these discovery results, we selected ten candidate metabolites based on the smallest p-values among metabolites exhibiting a fold-change greater than 1.5. The aim of the present study is to validate these ten differential metabolite levels in an independent cohort of Chilean patients with gallbladder cancer and gallstone disease, and to assess the transferability of these findings to other patient populations.
Key facts
- Study ID
- NCT07744477
- Run by
- Centre Paul Strauss
- People needed
- 230
- Starts
- 2019-12-01
- Expected to finish
- 2026-01-31
- Last updated by the study team
- 2026-08-04
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients with gallstones and cancer-free OR - Patients with gallbladder cancer
- Patients aged 18 years or older
You may not qualify if…
- Patients younger than 18 years
Where it is running
- Complejo Hospitalario Viedma — Cochabamba, Bolivia
- Hospital del Norte — Cochabamba, Bolivia
- Hospital Obrero No. 2 (Caja Nacional del Seguro Social) — Cochabamba, Bolivia
- Instituto Gastroenterológico — Cochabamba, Bolivia
- Instituto Oncológico Nacional — Cochabamba, Bolivia
- Hospital Clínico de Magallanes — Arica, Chile
- Hospital Regional de Arica — Arica, Chile
- Hospital Regional de Concepción, — Concepción, Chile
- Hospital De Puerto Montt — Port Montt, Chile
- Hospital Regional de Rancagua — Rancagua, Chile
- Clínica Alemana de Santiago — Santiago, Chile
- Fundación Arturo López Perez (FALP) — Santiago, Chile
- Hospital Barros Luco — Santiago, Chile
- Hospital Clínico Universidad de Chile — Santiago, Chile
- Hospital del Salvador — Santiago, Chile
- Hospital El Pino — Santiago, Chile
- Hospital Padre Hurtado — Santiago, Chile
- Hospital San Borja — Santiago, Chile
- Hospital San Juan de Dios — Santiago, Chile
- Hospital Sótero del Río — Santiago, Chile
- Hospital Regional de Talca — Talca, Chile
- Clínica Alemana de Temuco — Temuco, Chile
- Complejo Asistencial Padre Las Casas — Temuco, Chile
- Hospital Regional de Temuco — Temuco, Chile
- Statistical Genetics Research Group, Institute of Medical Biometry, University of Heidelberg — Heidelberg, Germany
Full record on ClinicalTrials.gov
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