CRPS-Hand: Contrast + Compression vs Whirlpool

Recruiting now · Not applicable

Conditions studied: Complex Regional Pain Syndrome I (CRPS I)

In brief

This randomized controlled trial aims to evaluate and compare the effectiveness of combined contrast therapy with intermittent compression and whirlpool therapy in patients with post-traumatic CRPS-I of the hand and wrist, using objective outcome measures of pain, edema, and functional status.

Key facts

Study ID

NCT07744269

Run by

Ankara Etlik City Hospital

People needed

50

Starts

2026-05-01

Expected to finish

2027-07-30

Last updated by the study team

2026-08-04

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients diagnosed with Complex Regional Pain Syndrome Type 1 (CRPS-I) according to the Budapest Criteria
• Age between 18 and 80 years
• CRPS developed following upper extremity trauma (e.g., hand or wrist fracture, soft tissue injury)
• Symptom duration less than 3 months (subacute stage)
• Ability and willingness to provide written informed consent and voluntarily participate in the study

You may not qualify if…

• Patients diagnosed with Complex Regional Pain Syndrome Type 2 (CRPS-II) or with evidence of peripheral nerve injury
• History of peripheral neuropathy, Raynaud's phenomenon, or vascular circulation disorders
• Presence of impaired skin integrity, open wounds, infection, or dermatological disease in the affected area
• History of cold or heat intolerance, cold urticaria, or hypersensitivity to thermal modalities
• Active infection or severe edema in the affected extremity
• Presence of serious systemic diseases (cardiovascular, pulmonary, renal, or neurological)
• Receipt of similar physical therapy or modality-based treatment within the past 3 months

Where it is running

• Etlik City Hospital, Department of Physical Medicine and Rehabilitation — Ankara, Yenimahalle, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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