A Clinical Trial of MK-1406 in Healthy Participants (MK-1406-008)

Starting soon · Phase 1

Conditions studied: Healthy

In brief

The purpose of this trial is to compare what happens to MK-1406 in the body of healthy participants when it is given as 2-injections and 3-injections. Researchers also want to learn about the safety of MK-1406 and if people tolerate it.

Key facts

Study ID

NCT07743151

Run by

Merck Sharp & Dohme LLC

People needed

400

Starts

2026-09-15

Expected to finish

2027-02-05

Last updated by the study team

2026-08-03

Who can join

Age: 18 and older, up to 64. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• The main inclusion criteria include but are not limited to the following:
• Is in good health
• Has body mass index (BMI) 18.0 to 32.0 kg/m\^2

You may not qualify if…

• The main exclusion criteria include but are not limited to the following:
• History of clinically significant endocrine, Gastrointestinal (GI), cardiovascular, hematological, hepatic, immunological, renal, respiratory, genitourinary, or major neurological (including stroke and chronic seizures) abnormalities or diseases
• History of cancer (malignancy)

Full record on ClinicalTrials.gov

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