Efficacy of Topical Tyrosine Versus Topical 5-Fluorouracil With Fractional Erbium YAG Laser

Recruiting now · Early Phase 1

Conditions studied: Focal Vitiligo

In brief

Vitiligo is an autoimmune disorder affecting the skin, specifically targeting pigment-producing melanocytes, leading to noticeable regions of depigmentation characterized by white spots. It is a widely prevalent skin disorder globally, affecting males and females almost equally, although it is reported slightly more frequently in females. In more than 60% of patients, the disease begins before the age of 30 and It has an estimated prevalence of roughly 0.2-2% across various populations, with around 0.4% in the European-derived white (EUR) population.

Key facts

Study ID

NCT07742982

Run by

Aswan University

People needed

40

Starts

2026-06-01

Expected to finish

2027-06-10

Last updated by the study team

2026-08-03

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients with focal vitiligo

You may not qualify if…

• Pregnancy.
• Lactation.
• Patients with segmental vitiligo.
• Patients with autoimmune disease including thyroiditis.
• Patients with chronic systemic diseases,such as anemia ,diabetes mellitus, immunosuppression, or chronic infections.
• Patients with active skin infections.

Where it is running

• Aswan University Hospital — Aswān, Egypt (enrolling)

Full record on ClinicalTrials.gov

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