How Differences in the Composition of Microorganisms in the Soil Affect the Microorganisms in the Human Gut, Through the Vegetables That Grow in it: a Process Pilot Study With Healthy Participants
Starting soon · Not applicable
Conditions studied: Pilot Study
In brief
There are two objectives for this clinical trial. The first is to test whether, with the current logistics and study setup it is possible to perform the study well and see where there might be bottlenecks we couldn't predict. The second objective is to investigate the relation between the composition of the microorganisms in the soil, the crops that grow in that soil, and the human gut. During the study participants will drink three vegetable smoothies a day, for two periods of one week. The only difference between the two periods is whether the vegetables come from a farm with a low diversity of microorganisms in the soil or a high diversity. Participants will be asked to give blood samples and turn in fecal samples before and after each period.
Key facts
- Study ID
- NCT07742319
- Run by
- Leiden University Medical Center
- People needed
- 10
- Starts
- 2026-08-01
- Expected to finish
- 2026-09-01
- Last updated by the study team
- 2026-08-03
Who can join
Age: 18 and older, up to 70. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Aged 18 to 70 years
- Written informed consent
- Inhabitant of Leiden
You may not qualify if…
- Any documented causes of chronic disease
- Suspicion of or present excessive alcohol use defined as >2 units/day (>14/week)
- Recent use (<3 months) of antibiotics
- Any known food allergy or restriction, or following a vegan/vegetarian diet
- Use of possible drugs interfering microbiota or recent (< 3 months) changes in dosages
- A psychiatric, addictive or any other disorder that compromises the participants ability to understand the study content and to give written informed consent for participation in the study
Where it is running
- Leids Universitair Medisch Centrum — Leiden, South Holland, Netherlands
Full record on ClinicalTrials.gov
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