Impact of Non-surgical Periodontal Treatment on Targeted Metabolomics

Recruiting now · Not applicable

Conditions studied: Periodontitis

In brief

A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment by means of minimally invasive approach MINST or Q-SI (quadrantwise) approach in subjects with periodontitis on targeted metabolomics in gingival crevicular fluid

Key facts

Study ID

NCT07740447

Run by

University of Catania

People needed

60

Starts

2026-05-04

Expected to finish

2026-12-18

Last updated by the study team

2026-07-31

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of Periodontitis

You may not qualify if…

• Periodontal treatment during the last 6 months
• Use of antibiotics, NSAIDs, and immunosuppressants during the last 6 months
• Pregnancy

Where it is running

• AOU Policlinico G. Rodolico — Catania, Italy, Italy (enrolling)

Full record on ClinicalTrials.gov

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