Serrated Inferior Turbinate Variation and Sinonasal Findings on CBCT

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Conditions studied: Nasal Cavity, CBCT Segmentation

In brief

regulate nasal airflow, humidify and filter inspired air. Serrated inferior turbinate is a rare anatomical variation characterized by an irregular, serrated appearance of the inferior turbinate bone. Although this variation has been described in radiological studies, its possible relationship with maxillary sinus mucosal changes and other sinonasal anatomical features remains unclear. This retrospective observational study aims to evaluate the relationship between serrated inferior turbinate variation and maxillary sinus mucosal thickness, mucosal abnormalities, and other sinonasal anatomical structures using cone-beam computed tomography (CBCT) images. CBCT images obtained from patients who underwent imaging for routine diagnostic purposes will be retrospectively reviewed. The presence of serrated inferior turbinate variation, maxillary sinus findings, inferior turbinate measurements, and nasal septum characteristics will be evaluated. The study aims to improve understanding of the radiological significance of serrated inferior turbinate variation and to provide information that may contribute to more accurate evaluation and reporting of sinonasal anatomical variations.

Key facts

Study ID

NCT07739927

Run by

Recep Tayyip Erdogan University Training and Research Hospital

People needed

105

Starts

2026-07-15

Expected to finish

2026-08-30

Last updated by the study team

2026-07-31

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Individuals aged 18-75 years.
• Patients who underwent cone-beam computed tomography (CBCT) imaging for routine diagnostic purposes between January 2025 and June 2026.
• CBCT images including both maxillary sinuses, nasal cavity, ostiomeatal complex, and inferior turbinates.
• CBCT images with sufficient diagnostic quality and clearly visible anatomical boundaries for evaluation and measurements.
• CBCT images in which the anatomical landmarks required for nasal septal deviation angle measurement (crista galli, maxillary spine, and the most deviated point of the nasal septum) can be clearly identified.

You may not qualify if…

• Patients with maxillofacial trauma, fractures, or conditions affecting the midface anatomy.
• Patients with congenital craniofacial anomalies (e.g., cleft lip and palate) or syndromes affecting facial anatomy.
• Patients with a history of sinonasal, inferior turbinate, or maxillary sinus surgery.
• CBCT images with insufficient diagnostic quality, motion artifacts, or metal artifacts preventing accurate evaluation.
• Patients with pathological lesions affecting the maxillary sinus or nasal cavity anatomy, including cysts, tumors, or aggressive inflammatory lesions.
• CBCT findings suggestive of fungal sinusitis, including heterogeneous hyperdense contents, calcifications, bone expansion, or invasive changes.

Full record on ClinicalTrials.gov

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