Acceleromyography Versus Electromyography for Neuromuscular Recovery Assessment at the End of Surgery

Starting soon

Conditions studied: Neuromuscular Blockade, Cholecystectomy

In brief

This prospective observational study aims to evaluate the agreement between acceleromyography and electromyography for measuring train-of-four (TOF) ratio at the end of surgery before reversal of neuromuscular blockade. Adult patients undergoing elective laparoscopic cholecystectomy under general anesthesia with non-depolarizing neuromuscular blockade will undergo simultaneous TOF measurements using both monitoring methods. The study will assess the agreement between the two techniques, estimate measurement bias and limits of agreement, and determine the frequency of clinically relevant disagreement that could affect assessment of neuromuscular recovery and safe extubation.

Key facts

Study ID

NCT07739862

Run by

Clínica Dávila

People needed

70

Starts

2026-08-01

Expected to finish

2027-01-01

Last updated by the study team

2026-07-31

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults aged 18 years or older.
• Scheduled for elective laparoscopic cholecystectomy under general anesthesia.
• Administration of non-depolarizing neuromuscular blocking agents.
• Written informed consent provided.

You may not qualify if…

• Pre-existing neuromuscular disease.
• Upper extremity abnormalities preventing neuromuscular monitoring.
• Contraindications to neuromuscular monitoring.
• Refusal or inability to provide informed consent.

Where it is running

• Clínica Dávila — Santiago, Santiago Metropolitan, Chile

Full record on ClinicalTrials.gov

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