A COMPARATIVE STUDY BETWEEN OPIOID-FREE GENERAL ANAESTHESIA AND OPIOID-BASED GENERAL ANAESTHESIA ON THE QUALITY OF RECOVERY IN PATIENTS UNDERGOING ELECTIVE LAPAROSCOPIC HYSTRECTOMY: A Randomized Trial

Starting soon · Not applicable

Conditions studied: Post Operative Recovery, Post Operative Nausea and Vomiting (PONV), Post Operative Analgesia

In brief

the intent of this study To compare the efficacy of opioid free general anaesthesia versus opioid based general anaesthesia to achieve enhanced recovery regarding post-operative pain and post-operative nausea and vomiting episodes in patients undergoing elective laparoscopic hysterectomy

Key facts

Study ID

NCT07739641

Run by

Ain Shams University

People needed

66

Starts

2026-08-22

Expected to finish

2027-04-20

Last updated by the study team

2026-07-31

Who can join

Age: 40 and older, up to 65. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Undergoing a scheduled laparoscopic hysterectomy surgery under general anaesthesia.
• Age group: 40-65 years old.
• BMI<35.
• ASA I-II.

You may not qualify if…

• Emergency hysterectomy.
• Allergy to any of the drugs used in the study.
• HR < 50 bpm (chronic treatment by beta blockers, heart block patients).
• Alcohol or drug abuse.
• Psychiatric disease.
• Liver impairment. Kidney impairment

Where it is running

• Ain Shams — Cairo, Abbasia, Egypt

Full record on ClinicalTrials.gov

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