Triage Performance and Physiological Predictors of Serious Illness in Febrile Children in the Pediatric Emergency Department

Recruiting now

Conditions studied: Fever, Triage, Pediatric Emergency Medicine, Serious Bacterial Infection, Sepsis

In brief

This multicenter prospective observational cohort study evaluates how well the initial triage category assigned by the Turkish Ministry of Health three-level color-coded triage system (Red-Yellow-Green) predicts serious clinical outcomes in children aged 0-18 years who present with fever to pediatric emergency departments. The study additionally assesses whether physiological parameters recorded at triage (heart rate, respiratory rate, oxygen saturation, capillary refill time, AVPU level of consciousness, and general appearance) provide independent and incremental prognostic value beyond the assigned triage category. Ten centers across Turkey will enroll consecutive eligible febrile children over a 3-month period. Routine clinical care and triage decisions are not altered by the study. The primary outcome is a composite serious clinical outcome. The study is reported in accordance with the STROBE and TRIPOD statements.

Key facts

Study ID

NCT07739004

Run by

TC Erciyes University

People needed

3000

Starts

2026-07-28

Expected to finish

2026-12-01

Last updated by the study team

2026-08-05

Who can join

Age: any, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 0-18 years
• Presentation to the pediatric emergency department
• Fever >=38.0 C at triage OR history of fever within the preceding 24 hours

You may not qualify if…

• Presentation due to trauma
• Elective visits
• Missing triage data
• Re-attendance within 72 hours for the same episode (only the first visit is included)

Where it is running

• Erciyes University Faculty of Medicine — Kayseri, Talas, Turkey (Türkiye) (enrolling)
• Adana City Training and Research Hospital — Adana, Turkey (Türkiye) (enrolling)
• Cukurova University Faculty of Medicine — Adana, Turkey (Türkiye) (enrolling)
• Akdeniz University Faculty of Medicine — Antalya, Turkey (Türkiye) (enrolling)
• Osmangazi University Faculty of Medicine — Eskişehir, Turkey (Türkiye) (enrolling)
• Kartal Dr. Lutfi Kirdar City Hospital — Istanbul, Turkey (Türkiye) (enrolling)
• Dokuz Eylul University Faculty of Medicine — Izmir, Turkey (Türkiye) (enrolling)
• Kayseri City Hospital — Kayseri, Turkey (Türkiye) (enrolling)
• Celal Bayar University Faculty of Medicine — Manisa, Turkey (Türkiye) (enrolling)
• Tokat University Faculty of Medicine — Tokat Province, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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