Treatment of Mandibular Class II Furcation With Different Types of Biomaterials in Humans
Completed · Not applicable
Conditions studied: Periodontal Furcation Lesions
In brief
This randomized controlled clinical trial aims to determine which biomaterial combination yields superior clinical and tomographic outcomes in the treatment of mandibular class II furcation defects. In addition, modifications of gingival phenotype in the furcation area will be assessed.
Key facts
- Study ID
- NCT07738705
- Run by
- Lake Erie College of Osteopathic Medicine
- People needed
- 48
- Starts
- 2025-04-18
- Expected to finish
- 2026-07-26
- Last updated by the study team
- 2026-07-31
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adults diagnosed with Stage III or Stage IV periodontitis presenting with at least one mandibular molar with a Class II furcation defect requiring regenerative surgical treatment.
- Ability and willingness to provide written informed consent.
- Medically stable and able to undergo periodontal surgery.
- Willingness to comply with all study procedures and follow-up visits.
You may not qualify if…
- Stage I or Stage II periodontitis.
- Current smokers.
- Uncontrolled diabetes mellitus.
- Alcohol or substance use disorder.
- Chronic inflammatory diseases requiring continuous anti-inflammatory therapy.
- Current use of bisphosphonates or other medications associated with medication-related osteonecrosis of the jaw.
- Current use of medications known to induce gingival enlargement.
- Continuous use of systemic antibiotics or anti-inflammatory medications.
- Pregnant or breastfeeding individuals.
- Known allergy or hypersensitivity to the antibiotics, local anesthetics, or other study-related medications.
- Medical conditions that, in the investigator's judgment, make the participant unsuitable for periodontal surgery or study participation.
Where it is running
- LECOM School of Dental Medicine — Bradenton, Florida, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.