Evaluation of NIPSA Using Alloplastic Bone Graft and Cross-Linked Hyaluronic Acid in theTreatment of Intrabony Defects

Starting soon · Phase 1/Phase 2

Conditions studied: Intrabony Periodontal Defect, Periodontal Disease

In brief

Sixty patients will be selected from the outpatient clinic in the Oral Medicine and Periodontology Department, Faculty of Dentistry, Mansoura University, Egypt, according to preoperative clinical and radiographic data that will be used to evaluate the bone destruction pattern.

Key facts

Study ID

NCT07737678

Run by

Mansoura University

People needed

60

Starts

2026-08-01

Expected to finish

2027-03-01

Last updated by the study team

2026-08-04

Who can join

Age: 35 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age range: 35 to 65 years old.
• Patients diagnosed with stage III. Periodontitis
• Presence of isolated intrabony defect with PPD ≥ 6 mm, CAL ≥ 6 mm
• Intrabony defect depth ≥3 mm.
• Contained an intrabony defect, 3-wall intrabony defect.
• No periodontal treatment has been administered in the previous six months.
• Full-mouth plaque score ≤ 10%.
• Full-mouth bleeding score ≤ 10%. -

You may not qualify if…

• Smokers ≥ 10 cigarettes per day
• Patient with systemic disease.
• Pregnant or lactating patients.
• Patient who has traumatic occlusion.
• Noncompliant patient.
• Patient with multi-rooted teeth with class II \& III furcation involvement.

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.