Ultrasound-Guided Bilateral Transversalis Fascia Plane Block With vs Without Dexamethasone for Cesarean Delivery

Recruiting now

Conditions studied: Pain, Postoperative, Analgesia

In brief

Cesarean delivery is one of the most frequently performed surgical procedures worldwide, and effective postoperative pain management is essential to facilitate early mobilization, maternal-infant bonding, breastfeeding, and overall recovery. Ultrasound-guided transversalis fascia plane block (TFPB) has become an increasingly utilized component of multimodal analgesia following cesarean delivery because it provides effective somatic analgesia of the lower anterior abdominal wall. Adjuvants such as dexamethasone are frequently added to local anesthetics with the aim of prolonging block duration and improving postoperative analgesia; however, evidence regarding the clinical benefits of dexamethasone as an adjunct in TFPB remains limited. At our institution, bilateral ultrasound-guided TFPB is routinely performed for postoperative analgesia in patients undergoing cesarean delivery under spinal anesthesia, provided there is no contraindication and informed consent has been obtained. According to the treating anesthesiologist's routine clinical preference, dexamethasone may be added to the local anesthetic solution in some patients, whereas others receive local anesthetic alone. This retrospective cohort study will review the medical records and postoperative follow-up forms of patients who underwent cesarean delivery between November 1, 2025, and June 30, 2026. Postoperative analgesic outcomes, including opioid consumption, pain scores, time to first analgesic request, postoperative nausea and vomiting, recovery quality, and block-related adverse events, will be compared between patients receiving bilateral TFPB with dexamethasone and those receiving bilateral TFPB without dexamethasone. The findings are expected to provide real-world evidence regarding the potential contribution of dexamethasone to the analgesic efficacy of bilateral TFPB following cesarean delivery.

Key facts

Study ID: NCT07736989
Run by: Bahçeşehir University
People needed: 70
Starts: 2026-08-03
Expected to finish: 2026-08-15
Last updated by the study team: 2026-08-05

Who can join

Age: 18 and older, up to 50. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

Female patients aged 18-50 years.
Elective cesarean delivery performed under spinal anesthesia.
Bilateral ultrasound-guided transversalis fascia plane block performed for postoperative analgesia.
Availability of complete perioperative and postoperative follow-up records.

You may not qualify if…

Emergency cesarean delivery.
General anesthesia or combined spinal-epidural anesthesia.
Contraindication to transversalis fascia plane block.
Chronic opioid use.
Allergy to bupivacaine or dexamethasone.
Missing or incomplete postoperative follow-up data.

Where it is running

Bahcesehir Unişversity Medicalpark Goztepe hospital — Istanbul, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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