Effect of Amniotic Fluid Odor on Newborn Adaptation and Stress (AFO-NAS)

Recruiting now · Not applicable

Conditions studied: Postnatal Adaptation and Stress in Healthy Newborns Born by Cesarean Section

In brief

This study aims to determine whether exposure to the odor of a newborn's own amniotic fluid affects postnatal adaptation and stress in healthy newborns born by cesarean section. Newborns will be randomly assigned to either an intervention group or a control group. Newborns in the intervention group will be exposed to a sterile material moistened with their own amniotic fluid, while newborns in the control group will be exposed to a sterile material moistened with distilled water. Postnatal adaptation, physiological responses, and stress levels will be evaluated at predetermined time points.

Key facts

Study ID

NCT07736235

Run by

Aydin Adnan Menderes University

People needed

70

Starts

2022-12-16

Expected to finish

2026-08-15

Last updated by the study team

2026-07-30

Who can join

Age: 1 and older, up to 1. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Newborns delivered by cesarean section at 38-42 weeks of gestation
• Absence of a maternal history of high-risk pregnancy, including eclampsia, preeclampsia, or gestational diabetes

You may not qualify if…

• Birth weight below 2,500 g
• Birth weight of 4,000 g or above
• Apgar score below 7 at either 1 or 5 minutes after birth
• Presence of a congenital anomaly
• Admission to the neonatal intensive care unit during the early postnatal period

Where it is running

• Aydın Adnan Menderes University — Aydin, Efeler, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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