Effects of a Familiarization Protocol on Time to Exhaustion Performance

Starting soon · Not applicable

Conditions studied: Learning

In brief

Familiarization is widely recommended before exercise performance testing to improve measurement consistency and reduce learning effects. However, practical constraints often limit researchers to a single-or no-familiarization session, raising the possibility that improvements observed following an intervention may partially reflect increased familiarity with the testing procedure rather than genuine physiological adaptations. This issue may be particularly relevant for time-to-exhaustion (TTE) protocols, which have been reported to exhibit greater between-session variability than self-paced endurance tests. This exploratory analysis examined the magnitude of the familiarization effect during treadmill TTE testing by comparing a familiarization trial with a subsequent experimental trial. Linear mixed-effects models will be used to evaluate changes in TTE performance while accounting for pre-exercise fatigue and recovery, and between-session agreement was assessed using intraclass correlation coefficients and Bland-Altman analysis.

Key facts

Study ID

NCT07735507

Run by

University of Maia

People needed

20

Starts

2026-09-01

Expected to finish

2027-01-30

Last updated by the study team

2026-07-30

Who can join

Age: 18 and older, up to 40. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• healthy and physically active

You may not qualify if…

• current or recently injured participants

Full record on ClinicalTrials.gov

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