Role of Craving in the Transition Across Level of Addiction Severity: A Longitudinal Study.

Recruiting now

Conditions studied: Addiction

In brief

Substance/Alcohol Use disorders are defined as a loss of control over the use despite harmul consequences, as well as an intense and persistent urge to use, also called craving. Previous research has shown that craving is central among the diagnostic criteria for addiction, suggesting that it may be important in the onset and persistence of addiction. Addiction develops progressively, and it appears crucial to identify predictive markers of the transition from one level of severity to another over time. One hypothesis is that more closely linked symptoms (meaning symptoms that influence each other more) could be associated with greater severity and/or with the evolution of addiction severity over time. The aim of this project is to explore how the characteristics of the association between addiction symptoms (diagnostic criteria and symptoms as they occur in daily life), and the importance of craving relative to other symptoms, could serve as markers of different addiction severities and of the transition across these levels of severity.

Key facts

Study ID

NCT07734363

Run by

University of Bordeaux

People needed

700

Starts

2026-05-20

Expected to finish

2031-06-01

Last updated by the study team

2026-07-29

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Be over 18 years of age
• Identify a primary substance as a main problematic substance use.
• Be a regular user (at least twice a week in the last 30 days) of a primary substance (defined as their main problematic substance use).
• Present a current diagnosis of SUD for this primary substance according to DSM-5 criteria.

You may not qualify if…

• Medical, psychiatric or addiction condition that warrants immediate inpatient treatment intervention.
• Somatic, cognitive or other disorders preventing the use of the smartphone device (deafness, impaired vision, illiteracy….).
• Not being familiar with the use of smartphone
• Having a smartphone not compatible with the application and being unable to visit the laboratory to receive a loaner phone for the study.
• Difficulty in understanding and/or writing and/or reading French.
• Individuals participating in another study that includes an ongoing exclusion period.
• Be deprived of liberty due to an ongoing legal procedure.
• Be under legal protection.
• Be under guardianship or conservatorship.

Where it is running

• Université de Bordeaux CNRS UMR 6033 SANPSY — Bordeaux, France (enrolling)

Full record on ClinicalTrials.gov

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