Aerobic Exercise and Guided Imagery in Low Anterior Resection Syndrome

Recruiting now · Not applicable

Conditions studied: Rectal Cancer, Fecal Incontinence and Constipation, Aerobic Exercise, Guided Imagery Exercise, Pelvic Floor Physical Therapy, Pelvic Floor Muscle Training

In brief

Low Anterior Resection Syndrome (LARS) is a common complication after sphincter-preserving rectal cancer surgery and may negatively affect bowel function and quality of life. Although exercise has been shown to improve physical function and well-being in cancer survivors, evidence regarding its effects on LARS symptoms remains limited. This randomized controlled, multicenter study aims to evaluate the effects of an aerobic exercise program combined with guided imagery on bowel symptoms, quality of life, physical activity level, functional capacity, and psychological well-being in patients with LARS after rectal cancer surgery. Participants will be randomly assigned to either an intervention group receiving aerobic exercise and guided imagery in addition to standard care or a control group receiving standard care alone. Outcomes will be assessed at baseline and after the intervention period using validated clinical and patient-reported outcome measures. The findings of this study may contribute to the development of evidence-based rehabilitation strategies for improving bowel function and quality of life in patients with LARS following rectal cancer surgery.

Key facts

Study ID: NCT07732894
Run by: Biruni University
People needed: 50
Starts: 2025-12-30
Expected to finish: 2027-05-30
Last updated by the study team: 2026-07-29

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Upper-Middle-Lower Rectal Cancer
Having undergone surgery with TMJ
Having a protective ileostomy and a closed stoma
Being tumor-free according to laboratory reports (carcinoembryonic antigen), endoscopic findings, and abdominal ultrasonography and/or computed tomography data
Having at least minor LARS scores ("between 21" and "42") according to the -LARS scoring questionnaire
Having the ability to perform voluntary perineal traction contractions with perineal palpation
Being a volunteer with informed consent

You may not qualify if…

History of incontinence or defecation disorder not related to rectal cancer
Having another type of surgery for rectal cancer (Hartmann procedure, abdominoperineal excision, transanal endoscopic microsurgical resection, or sigmoid resection)
Deterioration in general health, neurological disease and/or physical disability
BMI > 30 kg/m2 (obese individuals)
Inability to answer questions or make interventions due to mental disorder

Where it is running

Memorial Bahçelievler Hospital — Istanbul, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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