Long-Term Outcomes Following HBOT

Recruiting now · Phase 2

Conditions studied: Traumatic Brain Injury, Post-Concussive Symptoms, Post-Traumatic Stress Disorder

In brief

This study is designed to better understand the long-term effects of hyperbaric oxygen therapy (HBOT). Our goal is to determine whether improvements after treatment are maintained over time and whether additional benefits appear months after treatment has ended. We will evaluate changes in cognitive function, mental health, and daily functioning to help strengthen the scientific evidence supporting the use of HBOT and guide future treatment recommendations.

Key facts

Study ID

NCT07732374

Run by

Summit Hyperbarics and Wellness

People needed

35

Starts

2026-06-18

Expected to finish

2027-06-18

Last updated by the study team

2026-07-28

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• At least 18 years of age.
• Veteran status
• Clinically diagnosed with a mTBI, PCS, PTSD, Anxiety, or Depression disorder.
• Successfully completed the parent Hyperbaric Oxygen Therapy (HBOT) intervention, consisting of the full study treatment protocol (40 HBOT sessions).
• Willing and able to read, understand, and provide written informed consent for participation in the 12-week follow-up study. Additionally, the Participant has clear consciousness and the ability to express self-feelings independently.
• Completed cognitive and psychological measurements.
• Clinical diagnoses cause significant impairment in social or occupational functioning or some other functional capacity.
• Stability on any current psychoactive medications (antidepressants, anti-anxiety medications, antipsychotics, stimulants, and mood stabilizers).

You may not qualify if…

• Acute medical illness or infection
• Severe or unstable physical disorders or major cognitive deficits
• Current manic, psychotic episodes, or serious suicidal ideations
• Non-English speakers
• Inability to attend scheduled follow-up visits
• Significant life events, new neurological injury, or new psychiatric diagnosis or hospitalization occurring after completion of the HBOT intervention that, in the opinion of the investigator, could confound cognitive, psychological, or quality-of-life outcomes.
• Participation in another interventional clinical study or receipt of a therapeutic intervention following completion of HBOT that could influence cognitive, psychological, or quality-of-life outcomes.

Where it is running

• Summit Hyperbarics and Wellness — Boise, Idaho, United States (enrolling)

Full record on ClinicalTrials.gov

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