Early Detection of Initial Caries Using Fluorescent Starch Nano-particles Compared With Salivary Biomarkers

Recruiting now · Not applicable

Conditions studied: Initial Caries

In brief

Dental caries is one of the most prevalent chronic oral diseases worldwide and remains a major public health concern. The disease begins with microscopic demineralization of enamel, which is reversible if diagnosed at an early stage. Therefore, early detection of carious lesions is essential to implement preventive and minimally invasive treatment strategies before irreversible tooth destruction occurs.

Key facts

Study ID

NCT07732127

Run by

Menoufia University

People needed

60

Starts

2026-07-01

Expected to finish

2027-07-01

Last updated by the study team

2026-08-07

Who can join

Age: 18 and older, up to 40. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Presence of at least one suspected initial enamel carious lesion.

You may not qualify if…

• Cavitated carious lesions
• Previous restorative treatment on the examined tooth
• Antibiotic therapy during the previous month,
• Systemic diseases affecting salivary secretion
• Xerostomia or salivary gland disorders

Where it is running

• Menoufia Dental Hospital — Shibīn al Kawm, Menoufia, Egypt (enrolling)

Full record on ClinicalTrials.gov

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