Effectiveness of Three Different Irrigation Methods During a Root Canal Treatment

Starting soon · Not applicable

Conditions studied: Three Canal Irrigation Methods and Their Comparison, Penetration of Irrigant in the Root Canal

In brief

This study aims to compare the effectiveness of three root canal irrigation techniques-Conventional Needle Irrigation (CNI), Side-Vented Needle (SVN), and Ultrasonic Irrigation (UI)-in achieving irrigant penetration into the apical third of the root canal. Since conventional irrigation often fails to adequately clean complex root canal anatomy, the study evaluates whether activation methods improve irrigant penetration. A randomized controlled trial will compare these three techniques using extracted single-rooted mandibular premolars. A radiopaque dye mixed with sodium hypochlorite will be used to measure irrigant penetration on digital radiographs, and the results will be statistically analyzed to determine the most effective irrigation method.

Key facts

Study ID

NCT07731594

Run by

Pakistan Institute of Medical Sciences

People needed

105

Starts

2026-07-12

Expected to finish

2026-12-26

Last updated by the study team

2026-07-28

Who can join

Age: 20 and older, up to 50. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Straight Canals
• Single Rooted 1st and 2nd mandibular premolars with closed apices

You may not qualify if…

• Mandibular premolars with open apices
• Mandibular premolars with curved or calcified canals

Full record on ClinicalTrials.gov

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