Zirconia-Reinforced Glass Ionomer Versus Injectable Giomer in Class V Restorations
Starting soon · Not applicable
Conditions studied: Class V Dental Caries, Type 2 Diabetes Mellitus, Giomer Technology; Injectable Resin Composite; Zirconia-Modified Glass Ionomer
In brief
This randomized controlled clinical trial aims to compare the clinical performance of zirconia-reinforced glass ionomer and injectable giomer restorations in Class V carious lesions among controlled type II diabetic against non-diabetics. One hundred Class V restorations will be allocated equally into four parallel groups according to restorative material and diabetic status. Clinical performance will be evaluated at baseline, 6, 12, and 18 months using the modified United States Public Health Service (USPHS) criteria. The primary outcome is restoration retention, while secondary outcomes include marginal adaptation, marginal discoloration, secondary caries, and postoperative sensitivity.
Key facts
- Study ID
- NCT07731308
- Run by
- Cairo University
- People needed
- 100
- Starts
- 2027-01-01
- Expected to finish
- 2029-01-01
- Last updated by the study team
- 2026-07-28
Who can join
Age: 22 and older, up to 55. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Male or Female participants from 22 to 55 years
- Controlled diabetic and non-diabetic patients consulting the outpatient clinic
- Patients categorized as moderate or high caries risk
- Patients willing to provide informed consent
- Co-operative patients agreeing to participate in the trial Inclusion Criteria for teeth
- Teeth with class V carious lesion classified according to the International Caries Detection and Assessment System (ICDAS II) as ICDAS code (4) or ICDAS code (5)
- Teeth with normal pulp vitality testing; no signs of inflammation or spontaneous pain before treatment
You may not qualify if…
- Patients with spontaneous or elicited pain from caries.
- Systemic illnesses other than diabetes.
- Severe bruxism/clenching.
- Temporomandibular joint disorders.
- Inability to return for recall visits/ Refusal to participate in the study.
- Pregnancy.
- heavy smoking.
- Lack of compliance.
- Exclusion criteria for teeth
- Teeth presenting with spontaneous or elicited pain
- A lack of normal pulp vitality testing
- Visible or clinical signs of pulpal/periapical inflammation before treatment.
- Class V carious lesions that are not classified as ICDAS code (4) or ICDAS code (5).
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.