Clinical Performance of Two HEMA-Free Universal Adhesive Systems
Starting soon · Not applicable
Conditions studied: Cervical Caries
In brief
This randomized controlled clinical trial aims to compare the 12-month clinical performance of two HEMA-free universal adhesive systems for restoring anterior cervical carious lesions. Participants will be randomly allocated (1:1) to receive restorations using either a two-bottle HEMA-free universal adhesive (G2-Bond Universal) or a one-bottle HEMA-free universal adhesive (BeautiBond Xtreme), both applied in self-etch mode. The primary outcome is restoration retention, while secondary outcomes include marginal adaptation, marginal discoloration, and postoperative sensitivity, evaluated at baseline (24 hours), 6 months, and 12 months using the modified USPHS criteria.
Key facts
- Study ID
- NCT07731061
- Run by
- Cairo University
- People needed
- 50
- Starts
- 2026-11-01
- Expected to finish
- 2028-01-01
- Last updated by the study team
- 2026-07-30
Who can join
Age: 18 and older, up to 55. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- . Patients aged from 18 to 55 years.
- Patients with cervical carious lesions on the labial surfaces of anterior teeth.
- Lesions classified as ICDAS 3 and 4.
- Patients with good general health.
- Patients able and willing to attend the follow-up visits at baseline, 6 months and 12 months.
You may not qualify if…
- Patients with severe or chronic periodontal disease.
- Patients with poor oral hygiene or uncontrolled plaque accumulation.
- Patients with bruxism or other parafunctional habits that may affect restoration survival.
- Non-vital teeth.
- Fractured or cracked teeth.
- Teeth with defective existing cervical restorations.
- Root caries extending beyond the restorative indication of the study.
- Pregnant or lactating patients.
- Patients with known allergy or hypersensitivity to any component of the adhesive systems or restorative material used in the study.
- Patients unable to attend the scheduled follow-up visits.
Full record on ClinicalTrials.gov
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