ESPB Versus SPSIPB for Quality of Recovery After Video-Assisted Thoracoscopic Surgery

Starting soon · Not applicable

Conditions studied: Postoperative Pain

In brief

Video-assisted thoracoscopic surgery (VATS) is associated with moderate to severe postoperative pain despite its minimally invasive nature. Ultrasound-guided erector spinae plane block (ESPB) and serratus posterior superior intercostal plane block (SPSIPB) are promising regional analgesic techniques for thoracic surgery; however, evidence directly comparing their effects on postoperative quality of recovery remains limited. This prospective, randomized, double-blind controlled trial aims to compare the effects of ESPB and SPSIPB on postoperative quality of recovery, measured by the Quality of Recovery-15 (QoR-15) questionnaire at 24 hours after surgery. Secondary outcomes include postoperative pain scores, tramadol consumption, time to first rescue analgesia, rescue analgesic requirement, postoperative nausea and vomiting, patient satisfaction, length of hospital stay, block-related complications, and perioperative hemodynamic parameters.

Key facts

Study ID

NCT07729488

Run by

Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

People needed

128

Starts

2026-08-01

Expected to finish

2026-12-30

Last updated by the study team

2026-07-27

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults aged 18-85 years.
• ASA physical status I-III.
• Scheduled for elective VATS under general anesthesia.
• Able to understand and complete the QoR-15 questionnaire.
• Written informed consent provided.

You may not qualify if…

• Refusal to participate or inability to provide written informed consent.
• Known allergy or contraindication to bupivacaine, paracetamol, dexketoprofen, or tramadol.
• Infection at the planned block injection site.
• Coagulopathy or ongoing anticoagulant therapy precluding regional anesthesia.
• Severe hepatic or renal insufficiency.
• Chronic opioid use or chronic pain requiring regular analgesic treatment.
• Previous thoracic surgery on the operative side.
• Pregnancy or breastfeeding.
• Cognitive impairment, psychiatric illness, or language barrier preventing completion of the QoR-15 questionnaire.
• Body mass index (BMI) >35 kg/m².
• Conversion from VATS to thoracotomy.
• Failed or incomplete regional block.

Where it is running

• Fatma Acil — Diyarbakır, Outside of the US, Turkey (Türkiye)
• Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital — Diyarbakır, Turkey, Turkey (Türkiye)

Full record on ClinicalTrials.gov

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