A Study of Strengthening Teen Brain Resilience Using Music During Cancer Treatment
Starting soon · Not applicable
Conditions studied: Childhood Hematopoietic and Lymphatic System Neoplasm, Childhood Malignant Solid Neoplasm, Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
In brief
This clinical trial tests the feasibility and acceptability of the Strengthening Teen Brain Resilience Using Music (STRUM) intervention to improve radiation induced cognitive decline for adolescents undergoing radiation therapy for cancer treatment. Adolescents treated with radiation therapy for cancer often experience persistent cognitive deficits and reduced brain resilience or the ability to preserve cognitive and emotional functioning despite stressors. Musical instrument training has been shown to enhance memory, academic skills, and emotional well-being in youth. Although guitars are often the most preferred instrument, ukuleles offer greater accessibility due to their simplicity, affordability, and suitability for younger users. The STRUM intervention consists of virtual active music therapy ukulele lessons, which may be a feasible and acceptable way to improve radiation induced cognitive decline for adolescents undergoing radiation therapy for cancer treatment.
Key facts
- Study ID
- NCT07729384
- Run by
- Mayo Clinic
- People needed
- 30
- Starts
- 2026-10-01
- Expected to finish
- 2028-11-01
- Last updated by the study team
- 2026-07-27
Who can join
Age: 12 and older, up to 17. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Aged 12-17 years at the time of enrollment
- Receiving initial radiation therapy (RT) for cancer treatment with curative intent at the Mayo Clinic Arizona
- Able to provide assent
- Able to read and write in English
- Have access to an electronic device with videoconferencing capability
You may not qualify if…
- Less than three-month prognosis
- Past history of RT
- Self-reported visual, hearing, or cognitive impairment impeding the ability to complete the STRUM intervention
- Prior receipt of ukulele or guitar lessons
- Actively receiving musical instrument lessons
Where it is running
- Mayo Clinic in Arizona — Scottsdale, Arizona, United States
Full record on ClinicalTrials.gov
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