Study of EO2002 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction

Starting soon · Phase 2 · Has a placebo group

Conditions studied: Corneal Edema, Fuchs, Fuchs Dystrophy, Fuchs' Endothelial Dystrophy, Endothelial Corneal Dystrophy, Corneal Endothelial Decompensation, Corneal Endothelial Cell Loss, Corneal Endothelial Disorder, Corneal Endothelial Dystrophy 1, Endothelial Cell Loss, Corneal, Pseudophakic Bullous Keratopathy, Pseudophakic Bullous Keratopathy (PBK)

In brief

This study will evaluate the safety and effectiveness of a single injection of EO2002 at one of two dose levels (150,000 or 500,000 magnetic human corneal endothelial cells \[mHCECs\]), compared with a placebo injection, in participants with corneal edema caused by corneal endothelial dysfunction.

Key facts

Study ID
NCT07729137
Run by
Emmecell
People needed
121
Starts
2026-09-01
Expected to finish
2028-02-01
Last updated by the study team
2026-07-29

Who can join

Age: 21 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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