The Effect of Olive Leaf Extract Supplementation on Training-induced Skeletal Muscle Functional and Molecular Adaptations in Healthy Volunteers
Starting soon · Not applicable · Has a placebo group
Conditions studied: Healthy Adult Participants, Exercise Training, Neuromuscular Adaptations, Nutritional Intervention
In brief
The goal of this study is to investigate the effect of combining olive leaf extract supplementation with endurance training (moderate intensity continuous training or sprint interval training). We hypothesize that OLE supplementation during training, as compared to training alone with placebo, will translate into better performance outcomes. More specifically, we hypothesize that the additional benefits of OLE supplementation on performance will be mediated by improved mitochondrial characteristics in skeletal muscle and increased neural activation.
Key facts
- Study ID
- NCT07729072
- Run by
- University of Lausanne
- People needed
- 60
- Starts
- 2026-09-01
- Expected to finish
- 2029-12-31
- Last updated by the study team
- 2026-07-27
Who can join
Age: 18 and older, up to 45. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Being between 18 and 45 years old
- Being healthy (assessed through the PAR-Q questionnaire).
- Being physically active, but not involved in any structured training program
- Being available for the study period.
You may not qualify if…
- If a participant answers positively to any YES/NO question in the PAR-Q health questionnaire. For questions requiring a precision, any positive answer will be reviewed by a medical doctor, who will determine the inclusion/exclusion of the participant.
- Having allergy to xylocaine
- Being pregnant.
Where it is running
- Bâtiment Synathlon, quartier UNIL-Centre — Lausanne, Switzerland
Full record on ClinicalTrials.gov
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