Intrathecal Pump Refills at Home or at the Hospital

Recruiting now · Not applicable

Conditions studied: Intrathecal Pump Refill

In brief

The IMPROVE study is a randomized, controlled, cross-over trial designed to compare intrathecal pump refills performed at home with those carried out in the hospital. Intrathecal drug delivery (IDD) is used in patients with chronic pain or severe spasticity. Use of IDD requires the performance of pump refills about 4-6 times a year which may be a burdensome and stressful experience for patients and their caregivers. Hospital visits can increase stress, pain, and caregiver strain, while early pilot studies suggest home-based refills may be both safe and more comfortable. Eighty-two adult patients in Belgium with an implanted intrathecal pump will be enrolled in the IMPROVE study. Each participant will undergo four refill procedures: two at home and two at the hospital, in randomized order.

Key facts

Study ID

NCT07727798

Run by

Moens Maarten

People needed

82

Starts

2025-10-15

Expected to finish

2028-10-01

Last updated by the study team

2026-07-27

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Actively receiving Intrathecal drug delivery
• Stable medication dosage for at least 3 months
• Dutch, French or English speaking adults

You may not qualify if…

• Life expectancy < 6 months
• Patients planned for but not yet received Intrathecal drug delivery implant
• No residence in Belgium

Where it is running

• UZ Brussel — Jette, Belgium (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.