AOSLO Imaging for the Study of Cellular Alterations in Retinal Neurodegeneration
Starting soon · Not applicable
Conditions studied: Glaucoma Associated With Other Ocular Disorders, Retina Disorder
In brief
Primary objective: \- Acquisition and analysis of images for non-medical purposes using the MONA IV system, an adaptive-optics-corrected scanning ophthalmoscope. Secondary objectives: * To measure the reproducibility of assessments; * To evaluate the detection of progressive changes.
Key facts
- Study ID
- NCT07725055
- Run by
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
- People needed
- 260
- Starts
- 2026-09-01
- Expected to finish
- 2030-04-01
- Last updated by the study team
- 2026-07-24
Who can join
Age: 10 and older, up to 79. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Patients:
- 100 subjects aged 10 to 79 years with a condition that may affect the inner retina (e.g., glaucoma, optic neuropathy, etc.)
- 100 subjects aged 10 to 80 years with a condition that may affect the outer retina (e.g., AMD, retinitis pigmentosa, etc.)
- Male or female
- Covered by health insurance
- Healthy volunteers:
- 30 subjects aged over 50 and under 80
- 30 subjects aged over 18 and under 50
- Male or female
- Healthy subjects with no known condition that directly or indirectly affects the structure of the eye
- Covered by health insurance
You may not qualify if…
- For all subjects:
- Inability to remain motionless on a standard ophthalmic chin rest. RETION_Protocol_v2.0 dated June 10, 2026_IDRCB: 2026-A00324-47 Page 10 of 44
- Subjects taking medications or suffering from a medical condition that could interfere with the evaluations planned under the protocol;
- Participants allergic to tropicamide in cases where pupil dilation is required. ☞ Wearing glasses or contact lenses to correct a refractive error is not considered an exclusion criterion.
Full record on ClinicalTrials.gov
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