Split Face Study of the Duration of Local Anesthetics - Fifth Arm

Starting soon · Phase 4

Conditions studied: This Study Will Focus on In-office Dermatological Procedures

In brief

This study will compare how long local anesthesia lasts when it is injected into different layers of the skin on the forearm. The investigators hypothesize that the numbing effect will last for different amounts of time depending on whether the medication is injected just under the skin or into the skin itself.

Key facts

Study ID

NCT07724418

Run by

Weill Medical College of Cornell University

People needed

50

Starts

2026-08-01

Expected to finish

2027-06-30

Last updated by the study team

2026-07-24

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Male or female ≥ 18 years of age
• Normal skin sensation at both nasal ala and volar forearms assessed by pinprick
• Ability to provide informed consent

You may not qualify if…

• Previous adverse reaction to local anesthetic or any components of the local anesthetics being evaluated
• Pregnant or breastfeeding volunteers (assessed by self-report)
• Patients taking monoamineoxidase inhibitors (MAOI) or antidepressants of the triptyline or imipramine types

Where it is running

• Weill Cornell Medicine — New York, New York, United States

Full record on ClinicalTrials.gov

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