Association Between Female Hormonal Profile and Wound Healing

Starting soon

Conditions studied: Wound Healing, Wound Healing Complication, Estradiol

In brief

The goal of this observational study is to assess the relationship between female hormonal status and postoperative wound healing in reduction mammaplasty. The main questions it aims to answer are: 1. Does wound healing differ depending on whether the operation takes place before or after ovulation in the menstrual cycle? 2. Does estradiol have a positive effect on wound healing? Participants with mammary hypertrophy will undergo reduction mammaplasty, and the investigators will measure their hormonal profile (LH, FSH, and estradiol) on the day of surgery.

Key facts

Study ID

NCT07724145

Run by

University Hospital, Geneva

People needed

84

Starts

2026-07-01

Expected to finish

2028-12-01

Last updated by the study team

2026-07-23

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Symptomatic breast hypertrophy
• Premenopausal

You may not qualify if…

• Previous breast reduction surgery
• Menopausal status
• Oral contraceptives
• Corticosteroid therapy
• History of breast cancer
• Active smoking and use of nicotine substitution products

Where it is running

• University Hospital of Geneva — Geneva, Switzerland

Full record on ClinicalTrials.gov

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