Acute Effects of Neurodynamics on Strength and Endurance in Athletes

Recruiting now · Not applicable

Conditions studied: Sciatic Leg Pain, Hamstring Muscle Tightness, Hamstring Muscle Strain, Hamstring Muscle Strength, Hamstring Injuries, Hamstring Injury Prevention, Hamstring Rupture, Sciatic Nerve Injury, Sciatic Radiculopathy, Lumbar Disc Herniation With Radiculopathy, Lumbar Disc Herniation

In brief

This study explores the acute effects of neurodynamics, an intervention commonly used by physical therapist to improve nerve mobility and decrease pain, on the strength and muscular endurance in the athletic population. This study aims to find if these interventions can maintain or promote strength and endurance in the hamstrings. The studies results will help physical therapist better prescribe exercise and hands-on treatment for hamstring and sciatic nerve related conditions and injuries.

Key facts

Study ID

NCT07721220

Run by

High Point University

People needed

45

Starts

2026-06-15

Expected to finish

2026-07-01

Last updated by the study team

2026-07-22

Who can join

Age: 18 and older, up to 30. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Participants must be between 18 and 30 years of age.
• Must be able to read, understand, and provide informed consent, in English.
• Must be currently participating in an organized sport (e.g. collegiate, club, or competitive recreational level) or engaging in structured resistance training and athletic conditioning for recreational sports events (e.g 5k, marathon, Crossfit, Hyrox, etc).
• Medically stable with no known contraindications to physical exertion.
• Cleared for participation in strength or maximal-effort isometric testing.
• Be able to perform lower extremity isometric testing without pain that limits maximal effort.
• Must have 2 lower extremities capable to producing full range knee flexion and extension range of motion.
• No medical condition that significantly alters lower extremity neuromuscular performance.
• No history of lower extremity surgery in the past 12 months.

You may not qualify if…

• Individuals younger than 18 or older than 30.
• Acute lower extremity injury in the last 12 weeks.
• Lower extremity surgery within the last 12 months.
• Pain in either lower extremity that would limit maximal physical exertion.
• History of neurological disorders, including but not limited to: Neuropathy, Stoke, MS, Parkinson's Disease, etc.
• Use of medications that significantly impact neuromuscular performance, strength or fatigue.
• No supplementation that affects neuromuscular performance, strength, or fatigue.
• Unable to read and understand English.
• Not in a vulnerable population: Pregnant, mentally or physically challenged, cognitively impaired.

Where it is running

• High Point University — High Point, North Carolina, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.