Impact of Exercise on Muscle Metabolism and Function for Persons With Parkinsons

Completed · Not applicable

Conditions studied: Parkinson

In brief

This investigation assesses the impact of a strengthening program on muscle metabolism in the gastrocnemius muscle (GM) and is an essential step in the establishment of future clinical intervention for the GM in people with Parkinson's disease (with healthy peers as the control group). The participants will be provided with a progressive GM strengthening program while monitoring muscle metabolism and functional changes before and after intervention.

Key facts

Study ID

NCT07720713

Run by

University of Texas Southwestern Medical Center

People needed

19

Starts

2022-04-27

Expected to finish

2023-06-30

Last updated by the study team

2026-07-22

Who can join

Age: 50 and older, up to 80. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 50-80 years of age, males and females, individuals with and without PD
• Hoehn and Yahr stages 1- 4 (if diagnosed with PD)
• Bilateral Heal Raise - minimum of 10 repetitions

You may not qualify if…

• Unable to walk for >5 minutes at a time with or without an assistive device
• Any comorbidity limiting exercise

Where it is running

• UT Southwestern Medical Center — Dallas, Texas, United States

Full record on ClinicalTrials.gov

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