Advanced HIV Re-engagement in Care

Starting soon · Not applicable

Conditions studied: Advanced HIV Disease

In brief

Adults who are hospitalized in Lusaka, Zambia, and found to have advanced HIV disease will be enrolled and randomly assigned to receive the ARC intervention or standard of care. All participants will then be followed through the end of the hospitalization and for up to 1 year after discharge from hospital.

Key facts

Study ID

NCT07720128

Run by

University of Alabama at Birmingham

People needed

724

Starts

2027-05-01

Expected to finish

2031-08-01

Last updated by the study team

2026-07-23

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Living with HIV
• Advanced HIV defined as CD4 <350 cells/mm3 or WHO stage 3 or 4 event
• Currently admitted to study hospital's internal medicine department

You may not qualify if…

• Planning to reside outside Lusaka after discharge
• Too sick to provide informed consent
• Known to have advanced cancer (defined as requiring chemo/radiation therapy or referred to hospice) other than Kaposi Sarcoma
• Known to have end stage kidney disease
• Known to have end stage liver disease
• No access to a telephone
• Currently incarcerated

Where it is running

• University Teaching Hospital — Lusaka, Zambia

Full record on ClinicalTrials.gov

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