The Effect of Different Positions Given to the Newborn During Delayed Cord Clamping on Physiological Indicators and Comfort

Enrolling by invitation · Not applicable

Conditions studied: Newborn Infant, Newborn Health, Delayed Cord Clamping

In brief

During intrauterine life, the fetus is connected to the mother via the placenta; with birth, the extrauterine adaptation process begins. The first six hours after birth are defined as the "adaptation period" for the newborn and consist of three stages. In this process, the first reactive period is particularly critical because the initial assessments determine the newborn's well-being. All organs, especially the respiratory and cardiovascular systems, are rapidly activated, and adaptation parameters are monitored. Evidence-based care interventions applied by midwives during this period directly affect the newborn's physiological stability and long-term health. The timing of umbilical cord clamping is a decisive factor in this adaptation. The World Health Organization recommends waiting at least 1 minute after birth for term and stable preterm infants, ideally with a delay of 1-3 minutes for clamping. Blood flow from the placenta to the baby continues for the first few minutes after birth. Therefore, not clamping the umbilical cord until 2-3 minutes have passed or until the cord pulse has completely stopped provides a physiological blood transfer. In this process, defined as "placental transfusion," a large portion of the blood passes to the baby within the first 3 minutes, contributing to an increase in circulatory volume and hemoglobin levels. In premature infants, stem cell transfer reduces complications and provides long-term benefits. In addition, this practice increases venous return, supporting heart filling and facilitating cardiorespiratory transition. In infants who undergo delayed clamping, oxygen saturation rises faster and irregular heartbeats are less common.

Key facts

Study ID

NCT07719751

Run by

Mersin University

People needed

120

Starts

2026-04-11

Expected to finish

2026-11-02

Last updated by the study team

2026-07-22

Who can join

Age: any. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• The newborn must have been born at term (≥37 weeks)
• Born from a singleton pregnancy
• Born vaginally
• The newborn must have been born alive
• The newborn must have spontaneous breathing
• The 1-minute Apgar score must be ≥7
• The mother must be able to communicate with the research
• The mother must have volunteered to participate in the study and given informed consent

You may not qualify if…

• Meconium-stained or foul-smelling amniotic fluid
• Episiotomy (3rd and 4th degree) and medical intervention during labor (vacuum, dystocia interventions, etc.)
• Suspicion of congenital anomalies or genetic diseases in the newborn
• History of known chronic diseases in the mother or baby (diabetes, hypertension, epilepsy, thyroid disease, etc.)

Where it is running

• Mersin University — Mersin, Turkey (Türkiye)

Full record on ClinicalTrials.gov

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