Treatment Costs of Kidney Injury in Patients Having Heart Surgery in the UK

Starting soon

Conditions studied: Acute Kidney Injury

In brief

Single-centre retrospective analysis of prospectively collected data with propensity matched scoring groups (AKI v/s non-AKI). Data collection from databases (or their equivalent): PATS Dendrite, Electronic Medical Records, TD-web (results Portal), MedTrack (ICU database), iSite (Radiology), SPY (Long-term status)

Key facts

Study ID

NCT07719569

Run by

The Royal Wolverhampton Hospitals NHS Trust

People needed

4600

Starts

2026-10-01

Expected to finish

2027-04-01

Last updated by the study team

2026-07-22

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Underwent elective or in-house urgent cardiac surgery at the Royal Wolverhampton NHS Trust between 1st January 2013 and 31st December 2025, excluding those who had surgery during 2020 and 2021 due to the confounding effect of COVID-19 on acute kidney injury incidence.
• Cardiopulmonary bypass (CPB) was utilised during the cardiac surgical procedure.
• A complete minimum dataset is available within the study databases, comprising: age, sex, history of diabetes, left ventricular ejection fraction (LVEF), surgical priority, pre-operative haemoglobin and serum creatinine (SCr) levels, type of cardiac surgery performed, CPB duration, EuroSCORE or logistic EuroSCORE, renal replacement therapy (RRT) use, and post-operative day 1 and/or day 2 and/or day 3 SCr values.

You may not qualify if…

• The procedure was performed as an emergency surgery.
• Required data fields are incomplete or unavailable.
• Surgery was performed off-pump, without the use of cardiopulmonary bypass.
• The patient was dialysis-dependent prior to surgery.
• The patient had a pre-operative estimated glomerular filtration rate (eGFR) of less than 20 mL/min/1.73 m².
• The cardiac procedure required deep hypothermic circulatory arrest (DHCA).
• The patient has exercised their right to opt out of research data use.

Where it is running

• The Royal Wolverhampton NHS Trust — Wolverhampton, West Midlands, United Kingdom

Full record on ClinicalTrials.gov

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