Zirconia Crowns Versus Extraction of Primary Anterior Teeth

Starting soon · Not applicable

Conditions studied: Early Childhood Caries (ECC)

In brief

Severely mutilated anterior primary teeth in preschool children are frequently managed by extraction. However, premature loss of anterior primary teeth has been associated with adverse functional, developmental and psychosocial outcomes, including impaired oral health-related quality of life (OHRQoL), speech concerns and negative self-image. Prefabricated zirconia crowns offer an aesthetic and durable restorative alternative for compromised anterior primary teeth. Despite increasing clinical use, comparative evidence evaluating zirconia crown restoration versus extraction under equivalent conditions using validated patient-centred, developmental and economic outcomes remains limited. This pragmatic, prospective, non-randomised controlled clinical study aims to compare zirconia crown restoration and extraction of severely mutilated anterior primary teeth performed under GA in preschool children. Outcomes include OHRQoL, parental satisfaction, child self-image, and speech development.

Key facts

Study ID

NCT07719478

Run by

Passant Nagy

People needed

60

Starts

2026-07-18

Expected to finish

2026-08-01

Last updated by the study team

2026-07-22

Who can join

Age: 3 and older, up to 5. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Children aged 3-5 years
• Presence of one or more decayed primary anterior teeth
• Written informed consent from parent or legal guardian

You may not qualify if…

• Craniofacial anomalies or genetic syndromes
• Diagnosed developmental delay or speech disorders
• Previous speech therapy
• Systemic disease contraindicating general anaesthesia

Full record on ClinicalTrials.gov

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