FST Analysis Supporting Timely Therapy and Risk Assessment Via Clinical Decision Support for Kids

Recruiting now

Conditions studied: Acute Kidney Injury, Renal Replacement Therapy, Pediatric Intensive Care Unit

In brief

The goal of this study is to learn whether adding a clinical decision support tool to the electronic medical record helps clinicians use the furosemide stress test in critically ill children at high risk for severe acute kidney injury (AKI). The main question it aims to answer is: Does implementing the decision support tool reduce fluid overload and help predict which children will receive dialysis? Researchers will identify children admitted to the pediatric intensive care unit who are at high risk for AKI using risk stratification and biomarker testing, then compare outcomes in the two years after the tool is introduced with the two years before.

Key facts

Study ID

NCT07718464

Run by

Children's Hospital Medical Center, Cincinnati

People needed

120

Starts

2026-05-27

Expected to finish

2028-06-01

Last updated by the study team

2026-07-22

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Admitted to the pediatric intensive care unit (PICU)
• Renal Angina Index (RAI) greater than or equal to 8 (RAI+)
• Urine NGAL greater than or equal to 150 ng/mL (NGAL+)

You may not qualify if…

• Receipt of renal replacement therapy prior to PICU admission

Where it is running

• Cincinnati Children's Hospital Medical Center — Cincinnati, Ohio, United States (enrolling)

Full record on ClinicalTrials.gov

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