Effect of macaúba Oil Combined With Green Exercises

Starting soon · Not applicable · Has a placebo group

Conditions studied: Stress Mental, Dyslipidemia, Obesity & Overweight

In brief

Animal model studies involving macaúba oil demonstrate beneficial effects on fat, oxidative stress, and adipogenesis. This study aims to evaluate lipid oxidation and mental stress levels in trained individuals following macaúba oil supplementation combined with outdoor exercise (green exercise) performed in a fasted state. The study will be randomized, double-blind, and placebo-controlled. Participants will receive either 400 mg of macaúba oil or placebo pills over an 8-week period while engaging in 5 km running sessions four times a week. Assessments of anthropometric parameters, body composition (DEXA), biochemical parameters, and heart rate will be conducted before and after the intervention, alongside the administration of a questionnaire regarding emotional well-being and perceived stress. At the end of the intervention, results will be analyzed using Kubios HRV 2.0 and GraphPad Prism (version 5.0) software; the Kolmogorov-Smirnov and Shapiro-Wilk tests will be applied to verify data normality, the Student's t-test for parametric data, and the Kruskal-Wallis and Wilcoxon-Mann-Whitney tests for non-parametric data.

Key facts

Study ID

NCT07715461

Run by

Federal University of Minas Gerais

People needed

60

Starts

2026-08-01

Expected to finish

2027-01-30

Last updated by the study team

2026-07-20

Who can join

Age: 35 and older, up to 59. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Aged 35 to 59 years
• Body mass index (BMI) below 30 m/kg²
• Body fat below 25%, with stability of body mass in the last six months
• Being physically active (performing moderate physical activity or <75 min / being vigorous physical activity)
• Being apparently healthy according to the Physical Activity Readiness Questionnaire.

You may not qualify if…

• Musculoskeletal injury that limits the ability to exercise at moderate intensity during the study period
• Use of supplements, anti-inflammatory drugs and/or analgesics during the study period
• Use of any therapy for muscle pain during the study period.

Where it is running

• Institute of Agricultural Science - Universidade Federal de Minas Gerais — Montes Claros, Minas Gerais, Brazil
• Federal University of Paraíba — João Pessoa, Paraíba, Brazil

Full record on ClinicalTrials.gov

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