Low Dose Radiotherapy for Osteoarthritis

Recruiting now · Not applicable

Conditions studied: Osteoarthitis

In brief

This single institution, multi-site, single arm prospective study will enroll patients with a history of OA and assess changes in pain and function after treatment with LDRT as measured by patient-reported outcomes.

Key facts

Study ID

NCT07715188

Run by

Abramson Cancer Center at Penn Medicine

People needed

113

Starts

2026-06-24

Expected to finish

2029-06-01

Last updated by the study team

2026-07-20

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 18 years or older
• Diagnosis of OA >3 months in hips, knees, hands, shoulders, ankles or elbows.
• Refractory to standard of care therapies for OA or those who are being considered for more aggressive interventional treatment such as joint replacement, but more conservative treatment is desired.
• Provision of signed and dated informed consent.

You may not qualify if…

• Unable to reasonably complete study instruments.

Where it is running

• Penn Presbyterian Medical Center — Philadelphia, Pennsylvania, United States (enrolling)
• Perelman Center for Advanced Medicine — Philadelphia, Pennsylvania, United States (enrolling)

Full record on ClinicalTrials.gov

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