Pharmacist-Assisted Titration of Rx to Implement Optimal Medical Therapy for Heart Failure

Starting soon · Not applicable

Conditions studied: Heart Failure, Heart Failure, Systolic

In brief

Many Veterans who are hospitalized with heart failure do not receive all the recommended heart medications at the right doses before they leave the hospital or in the weeks following discharge. This study tests whether a team of clinical pharmacists and cardiologists, working virtually, can improve heart failure medication prescribing for Veterans at VA medical centers. The pharmacist and cardiologist team reviews patient records and provides recommendations to the treating doctors and primary care providers caring for Veterans with heart failure. The goal is to increase use of guideline-recommended medications, which have been shown to improve survival, reduce hospitalizations, and improve quality of life.

Key facts

Study ID

NCT07714239

Run by

VA Office of Research and Development

People needed

585

Starts

2026-07-24

Expected to finish

2030-09-30

Last updated by the study team

2026-07-20

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Admission to a VA medical center or VA-paid community hospital within the preceding 3 months with a primary diagnosis of heart failure
• The primary study cohort will consist of those admitted to a VA medical center, while the secondary study cohort will consist of patients admitted to VA-paid community hospitals
• Left ventricular ejection fraction ≤ 40%
• Not on optimal guideline-directed heart failure medication classes or doses, as assessed in the electronic health record
• Receiving care within one of the 6 participating VA medical centers

You may not qualify if…

• Hemodynamic instability
• Receiving comfort care measures alone or enrolled in hospice

Where it is running

• Rocky Mountain Regional VA Medical Center, Aurora, CO — Aurora, Colorado, United States

Full record on ClinicalTrials.gov

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