Abstinence Reinforcement Therapy for Veterans Who Smoke Tobacco and Are Experiencing Homelessness

Starting soon · Not applicable

Conditions studied: Tobacco Use Disorder

In brief

Seventy to eighty percent of Veterans experiencing homelessness (VEH) smoke, which is four times the rate of the U.S. population and 2.5 times higher than among impoverished Americans. Smoking- related deaths among persons experiencing homelessness occur at double the rate seen among more stably housed people. The purpose of this study study is to evaluate the effectiveness of an intervention to help Veterans experiencing homelessness stop smoking. The intervention, called Abstinence Reinforcement Therapy + (ART+), includes telehealth-based counseling, smoking cessation aids, and mobile contingency management (mCM). mCM is an intervention in which participants are paid for smoking abstinence. 120 Veterans who smoke cigarettes and are experiencing homelessness will be randomly assigned to receive either ART+ or usual smoking cessation care. The primary outcome to be evaluated is the rate at which Veterans assigned to the ART+ condition report smoking abstinence and have their abstinence verified using salivary testing.

Key facts

Study ID

NCT07714200

Run by

VA Office of Research and Development

People needed

120

Starts

2027-03-01

Expected to finish

2030-09-01

Last updated by the study team

2026-07-20

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Are homeless
• Smoke at least 5 cigarettes daily with CO indicating current smoking at time of screening assessment
• Are willing to try to quit smoking in next 30 days

You may not qualify if…

• Have uncontrolled psychotic symptoms
• Have active substance dependence other than nicotine (participants in partial remission with at least one month sobriety will be included)
• Have severely impaired hearing or speech

Where it is running

• Durham VA Medical Center, Durham, NC — Durham, North Carolina, United States

Full record on ClinicalTrials.gov

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