Post-operative Cognitive Decline After Ambulatory Cataract Surgery in the Elderly Population

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Conditions studied: Post-Operative Cognitive Decline in Older Adults, Post-operative Cognitive Decline, Perioperative Neurocognitive Disorders, Cataract Surgery Anesthesia

In brief

Postoperative cognitive decline is a recognized complication following anesthesia and surgery in older adults; however, its incidence after ambulatory cataract surgery performed under sedation is not well understood. This prospective observational study aims to determine the proportion of patients aged 65 years and older who develop postoperative cognitive decline at 3 weeks and 3 months following ambulatory cataract surgery. Participants will complete a baseline Tele-Montreal Cognitive Assessment (T-MoCA) before surgery and repeat the assessment remotely at 3 weeks and 3 months after surgery. Demographic, medical, anesthetic, and procedural data will also be collected. The findings will improve understanding of postoperative cognitive outcomes in elderly patients undergoing ambulatory cataract surgery and help identify patients who may be at increased risk for postoperative cognitive decline.

Key facts

Study ID

NCT07714174

Run by

Samuel Lunenfeld Research Institute, Mount Sinai Hospital

People needed

300

Starts

2026-08-01

Expected to finish

2027-11-01

Last updated by the study team

2026-07-20

Who can join

Age: 65 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• All patients ages 65 and older

You may not qualify if…

• Inability to understand instructions in English
• Lack of access to a computer, tablet, smartphone, or internet access
• Patients with established cognitive deficit diagnoses (e.g. Alzheimer's, TBI, stroke)
• Patients with known psychiatric diagnoses
• Patients who have undergone any procedure or surgery requiring sedation, regional, neuraxial or general anesthesia within the past 6 months

Where it is running

• Kensington Eye Institute — Toronto, Ontario, Canada

Full record on ClinicalTrials.gov

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