Association Between Pain Catastrophizing and PONV in Laparoscopic Cholecystectomy Patients

Recruiting now

Conditions studied: Vomiting, Postoperative, Pain, Nausea and Vomiting, Postoperative, Pain Catastrophizing

In brief

This study aims to explore whether patients' tendency to exaggerate or focus on pain (pain catastrophizing) is related to experiencing nausea and vomiting after surgery. The study will include patients undergoing laparoscopic cholecystectomy. Before surgery, patients will answer questions measuring pain catastrophizing and rate their pain during intravenous cannulation. Nausea and vomiting will be assessed at various times during the first 24 hours after surgery. The results may help better understand how psychological factors affect postoperative symptoms.

Key facts

Study ID

NCT07712211

Run by

Trabzon Kanuni Education and Research Hospital

People needed

64

Starts

2026-01-15

Expected to finish

2027-04-01

Last updated by the study team

2026-07-17

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Adult patients aged 18-65 years
• American Society of Anesthesiologists (ASA) physical status I-II-III
• Scheduled for elective laparoscopic cholecystectomy
• Able to provide informed consent

You may not qualify if…

• Age <18 or >65 years
• Emergency surgery
• ASA physical status > III
• Pregnancy
• Chronic opioid use
• Known drug allergy
• Psychiatric disorders
• Neurological diseases (central or peripheral neuropathy)
• History of cerebrovascular disease (stroke)
• Chronic renal disease
• Chronic pulmonary disease
• Patients who refuse to participate

Where it is running

• Trabzon Kanuni Education and Research Hospital — Trabzon, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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