Comparison of the Concordance Between Digital Marking and Manual Marking for Toric Intraocular Lens Positioning

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Conditions studied: Cataract Surgeries

In brief

This cross-sectional comparative study evaluated patients from a single cataract center. In each eye, manual horizontal meridian axis line was marked on the cornea using the manual peripheral corneal marking technique (Horizontal Slit Beam Marking ), while the Verion digital image-guided navigation system provided a reference axis fixed at the horizontal meridian (0°/180°). The primary outcome measure was the difference in degrees between the digital marker and the manual marker horizontal meridian as measured intraoperatively. Agreement was assessed using Bland-Altman analysis, reporting the mean bias (systematic error) and 95% limits of agreement (LoA, mean ± 1.96 SD). A misalignment of ±10° was defined as the threshold of clinical significance.

Key facts

Study ID

NCT07710963

Run by

Thammasat University

People needed

100

Starts

2026-07-10

Expected to finish

2026-10-30

Last updated by the study team

2026-07-17

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• candidates for uncomplicated cataract surgery

You may not qualify if…

• irregular corneal astigmatism, lens subluxation, uveitis, glaucoma, trauma, history of retinal disease or optic neuropathy, previous intraocular or corneal surgery and corneal disease that could not be evaluated by the ARGOS or VERION systems

Full record on ClinicalTrials.gov

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