ERAS in Choledochal Cyst & Biliary Atresia

Recruiting now · Not applicable

Conditions studied: Choledochal Cyst Resection, Biliary Atresia, Kasai Portoenterostomy Status

In brief

This study aims to compare two feeding approaches after surgery for biliary atresia and choledochal cyst in children. Traditionally, children are kept without oral feeding for more than 48 hours after these operations until bowel activity returns. However, newer Enhanced Recovery After Surgery (ERAS) programs suggest that starting feeding earlier may help children recover faster. In this study, children undergoing surgery for biliary atresia or choledochal cyst will be randomly assigned to one of two groups. One group will start oral liquids within 24 hours after surgery and gradually progress to normal feeding as tolerated (early feeding group). The other group will receive conventional care, where feeding is started after more than 48 hours once bowel activity has returned. Researchers will compare both groups for postoperative complications such as wound infection and anastomotic leakage, as well as the duration of hospital stay. Additional observations will include vomiting, abdominal distension, need for reinsertion of a nasogastric tube, requirement for repeat surgery, and time taken to resume normal feeding. Participation in the study will not affect the standard surgical treatment provided. All children will receive routine perioperative care and will be monitored closely throughout their hospital stay and follow-up visits. The findings of this study may help determine whether early oral feeding is a safe and effective strategy to improve recovery and reduce hospitalization after pediatric hepatobiliary surgery.

Key facts

Study ID

NCT07709702

Run by

Muhammad Zubair Shoukat

People needed

100

Starts

2024-07-27

Expected to finish

2026-08-01

Last updated by the study team

2026-07-16

Who can join

Age: 0 and older, up to 14. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• All children diagnosed with choledochal cyst type I and IV on MRCP or CT scan, undergoing elective Roux-En-Y hepaticojejunostomy
• All children with provisional diagnosis of biliary atresia undergoing Roux-En-Y portoenterostomy

You may not qualify if…

• Patients with suspected biliary atresia not undergoing portoenterostomy after Per-op cholangiogram either due to ruling out of disease or advanced disease deemed candidates for liver transplant
• patients with history of Emergency surgery or external drainage of choledochal cyst
• Hemodynamically unstable patients after surgery
• Previous history of GI surgery

Where it is running

• University of Child Health Sciences, The Children's Hospital, Lahore — Lahore, Punjab Province, Pakistan (enrolling)

Full record on ClinicalTrials.gov

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