Salivary Cytokines, MMP-8 and Dental Caries in Osteoporosis Patients

Starting soon

Conditions studied: Osteoporosis, Dental Caries, Biomarkers, Matrix Metalloproteinase 8

In brief

This study examines saliva samples from patients with osteoporosis. The levels of cytokines and Matrix Metalloproteinase-8 (MMP-8) enzyme in saliva will be measured. Additionally, the dental caries status of participants will be evaluated. The aim of this study is to understand the relationship between osteoporosis and oral health. Only saliva samples will be collected from participants; no treatment or medication will be administered.

Key facts

Study ID

NCT07709247

Run by

Afyonkarahisar Health Sciences University

People needed

50

Starts

2026-07-10

Expected to finish

2027-07-10

Last updated by the study team

2026-07-16

Who can join

Age: 45 and older, up to 75. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Willing to give voluntary consent For Group 1, having been diagnosed with osteoporosis For Group 2, being systemically healthy and not having a diagnosis of osteoporosis/osteopenia

You may not qualify if…

• Having a chronic inflammatory or autoimmune disease Using glucocorticoids, anti-anxiety medications, antidepressants, or antiepileptic drugs Having been diagnosed with any malignancy Having any endocrine disease Having undergone periodontal treatment within the last 6 months

Full record on ClinicalTrials.gov

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