Two Intravenous Doses of Ketamine in Reducing the Oculocardiac Reflex in Adult Patients Undergoing Ophthalmic Surgery
Recruiting now · Not applicable
Conditions studied: Ketamine, Oculocardiac Reflex, Ophthalmic Surgery
In brief
This study aims to evaluate whether a lower dose of ketamine (0.5 mg/kg IV) may be as effective as a higher dose (0.75 mg/kg IV) in reducing oculocardiac reflex (OCR) incidence in adult patients undergoing ophthalmic surgery.
Key facts
- Study ID
- NCT07708740
- Run by
- Cairo University
- People needed
- 40
- Starts
- 2026-07-01
- Expected to finish
- 2027-12-30
- Last updated by the study team
- 2026-07-16
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age from 18 to 65 years old.
- Both sexes.
- American Society of Anesthesiologists (ASA) physical status I, II.
- Scheduled for elective ophthalmic surgery involving extraocular muscle traction under general anesthesia.
You may not qualify if…
- Ketamine contraindications (e.g., hypersensitivity, uncontrolled hypertension)
- History of cardiac arrhythmia or conduction disorder
- Glaucoma or raised intraocular pressure
- ASA status greater than II
- Patient refusal.
Where it is running
- Cairo University — Cairo, Egypt (enrolling)
Full record on ClinicalTrials.gov
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