UPRIGHT-PRO: Prospective Development Study of Upright Proton Therapy

Starting soon

Conditions studied: Proton Therapy

In brief

This study is being done to evaluate whether cancer patients can safely and reliably receive proton radiation therapy while positioned upright. Proton therapy is an established form of radiation treatment, and the upright treatment system used in this study has been cleared by the U.S. Food and Drug Administration. The intent of this protocol is to observe the treatment methods, doses, and outcomes for the initial cohorts of patients treated with this upright device. This study will support research activities and evaluate feasibility as needed. Results of this study will be reported in the scientific literature but the investigators do not intend to report to the FDA for a new use or indication or change to the labeling; nor are the investigators required to do so.

Key facts

Study ID

NCT07708636

Run by

Stanford University

People needed

450

Starts

2026-09-01

Expected to finish

2027-09-01

Last updated by the study team

2026-07-16

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Any cancer patient (children and adults) recommended for proton therapy.
• Participation in other clinical trials is allowed (including randomized trials of protons versus other treatments)

You may not qualify if…

• Any patient that doesn't meet the inclusion criteria

Where it is running

• Lucile Packard Children's Hospital Stanford — Palo Alto, California, United States
• Stanford University — Palo Alto, California, United States

Full record on ClinicalTrials.gov

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